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2020 Central Clinical School Public Lecture: Sudden Unexpected Death in Epilepsy (SUDEP): How translational research on epilepsy is finding answers

You are invited to attend the annual CCS public lecture. In 2020, the lecture will be presented by Professor Terry O'Brien, Head of Central Clinical School.

Epilepsy is a lifelong neurological condition estimated to affect over 65 million people worldwide, with approximately 150,000 Australians living with active epilepsy. Epilepsy is a potentially life-threatening disorder, with a standardised mortality of >3 times that of the general population. The most common epilepsy-related cause of premature mortality is Sudden Unexpected Death in Epilepsy (SUDEP), with or without evidence for a seizure in whom another cause is not found. It is estimated that 50-100 Australians each year die from SUDEP. It often occurs in young, otherwise healthy individuals, and with people with epilepsy having up to 40 times greater risk of dying suddenly who aged-matched controls without epilepsy. We are researching the mechanisms underlying SUDEP, to understand how uncontrolled seizures result in a disturbance of cardiorespiratory function which can cause sudden death. and develop intervention strategies to reduce the risk of SUDEP.

About our speaker

Professor Terry O'Brien is Head of Monash University's Central Clinical School and Program Director Alfred Brain and Deputy Director of Research, Alfred Health. He is a specialist in neurology and clinical pharmacology, with particular expertise in epilepsy and neurodegenerative diseases, neuropharmacology, pre-clinical and clinical drug development, and in-vivo imaging in animal models and humans. Professor O'Brien leads a large translational research team undertaking both basic studies and clinical studies on epilepsy and related brain diseases.

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Oct 29, 2020 06:00 PM in Canberra, Melbourne, Sydney